This medication is compounded by a licensed 503A pharmacy in accordance with Section 503A of the Federal Food, Drug & Cosmetic Act, and may only be dispensed pursuant to a valid, patient-specific prescription issued by a licensed healthcare practitioner following an individualized medical evaluation. The FDA does not review or approve compounded medications, including compounded tirzepatide, for safety, effectiveness, or quality. Compounded tirzepatide has not been FDA-approved for weight loss or any other indication, though peer-reviewed and third-party research suggests potential clinical benefits. Individual results will vary. This compounded formulation is not affiliated with, endorsed by, reviewed by, or intended to replace any FDA-approved product manufactured by Eli Lilly and Company. EOS Health and its pharmacy partners have no affiliation with Eli Lilly and Company.

EOS Metabolic

Compounded Tirzepatide + B12

From

319

/ month

Compounded Tirzepatide + B12 combines a dual-action GLP-1 and GIP medication with vitamin B12 in a single weekly injection. The tirzepatide works to regulate blood sugar, curb appetite, and slow digestion, while added B12 helps maintain the energy levels that keep an active routine on track through weight loss.

Key Features

Significant Weight Loss: Clinical studies of tirzepatide have demonstrated an average body weight reduction of 15% to 22% when combined with lifestyle modifications.

Steady Daily Energy: Added vitamin B12 supports red blood cell production and energy metabolism, helping offset the fatigue that can accompany a reduced-calorie routine.

Enhanced Appetite Suppression: Dual-receptor activation signals the brain to increase satiety, helping patients manage portion sizes naturally.

Delayed Gastric Emptying: It slows the digestive process, prolonging fullness and minimizing cravings throughout the day.

Blood Sugar Control: By stimulating insulin secretion and reducing glucagon production, it stabilizes blood sugar and prevents post-meal energy crashes.

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Benefits

Clinically proven. Personally delivered.

GLP-1 receptor agonists are among the most effective tools in modern weight management — backed by years of clinical data and real-world results.

Beyond the scale

Steadier blood sugar, better energy, and improved metabolic markers come with the weight.

Clinically proven results

GLP-1 protocols backed by years of clinical data, with meaningful results for most patients within weeks.

Clinician-Supervised

Board-certified physicians review your intake, personalize your starting dose, and stay accessible throughout your treatment journey.

Once-Weekly Dosing

A single small injection per week. No daily pills, no complicated schedules — just one moment that fits into your routine.

Preserves lean muscle

The protocol favors fat loss while helping you hold onto the muscle that keeps you strong.

Preserves Lean Muscle

Unlike crash diets, GLP-1 therapy helps your body preferentially burn fat while maintaining the muscle mass that keeps you strong.

FAQs

Common questions, answered.

Why is vitamin B12 added to compounded tirzepatide?

B12 is added to support energy metabolism during weight loss. As appetite drops and calorie intake falls on tirzepatide, some patients notice lower energy. Vitamin B12 plays a central role in red blood cell formation and in converting food into usable energy, so including it in each dose helps you stay active while the medication does its work.

Will the added B12 help with the fatigue some people feel on tirzepatide?

It can. Reduced food intake and rapid weight loss sometimes leave patients feeling run down, and low B12 levels make that worse. Compounding B12 into each weekly dose helps maintain healthy levels and supports steady energy. It is not a stimulant, and individual results vary from person to person.

Do I need a separate B12 shot with this formula?

No. The B12 is compounded directly into your weekly tirzepatide dose, so it is delivered in the same injection. There are no extra shots, vials, or schedules to manage. Your EOS clinician reviews your health history before prescribing to confirm the combined formula is right for you, and full details are in the Important Safety Information.

What happens if I'm not approved for the medication?

If you are not prescribed the desired medication from our team of medical providers, you will be notified and receive a full refund for all cost incurred. This includes a cancellation of any subscription memberships you selected.

What is the administration and dosage protocol?

EOS Health's approach to both oral and injectable tirzepatide administration involves a personalized dosage strategy. The medication starts at a lower dose and is gradually increased based on your body's response to minimize side effects. You will receive comprehensive instructions on how to self-administer the medication, ensuring comfort and confidence.

For oral tirzepatide:
- Administered using an oral syringe, which dispenses rather than injects.
- Measure the dose by pulling the plunger until you reach the appropriate volume as marked on the syringe, and administer it underneath the tongue.

You will receive comprehensive instructions on how to self-administer the medication, ensuring comfort and confidence in managing your medication. Regular follow-ups with your healthcare provider will help monitor your progress and adjust the dosage as needed to optimize your results and minimize side effects.

Disclaimer: Individual results may vary. Always consult with your healthcare provider before starting any new medication to ensure it is appropriate for your condition. Follow your healthcare provider's instructions for dosage and administration. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Not approved by the FDA for safety or efficacy. Prescription required.

How does tirzepatide work?

Tirzepatide activates both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, which help regulate blood sugar levels and reduce appetite.

Are there alternatives to compounded tirzepatide?

Yes, FDA-approved versions of tirzepatide—such as Mounjaro or Zepbound—should be considered as an alternative option.

What are common side effects of tirzepatide?

Common side effects of tirzepatide include nausea, vomiting, diarrhea, constipation, abdominal pain, decreased appetite, injection site reactions (such as redness, swelling, or pain), fatigue, and gastrointestinal issues like heartburn, gas, and bloating. Serious side effects, although less common, can include thyroid tumors, pancreatitis, and severe allergic reactions. Always consult your healthcare provider for personalized advice and to report any side effects.

Is compounded tirzepatide FDA-approved?

Compounded tirzepatide is not approved nor evaluated for safety, effectiveness, or quality by the FDA.

Brand-name medications such as Zepbound® (tirzepatide) and Mounjaro® (tirzepatide) are FDA-approved and not compounded. Compounded versions of tirzepatide are not affiliated with, endorsed by, approved by, or intended to replace the FDA-approved products manufactured by Eli Lilly.

How much weight can I lose on tirzepatide?

People lost an average of over 20% bodyweight in a 72-week clinical trial study of tirzepatide, but not without lifestyle changes. Along with a reduced calorie diet and increased exercise. In a 72-week clinical study of tirzepatide, adults with obesity and weight-related medical problems achieved 20.9% weight loss.

Can I start on a higher dosage?

If you're currently taking the medication and switching from another provider, you can choose to maintain your current dose, increase it, or decrease it. This information is asked during the ordering process to ensure you're purchasing the correct medication for you.

What is Compounded Tirzepatide?

Compounded tirzepatide is a medication created by licensed compounding pharmacies, customized for individual patient needs. It is prepared with tirzepatide and formulated to support healthy blood sugar regulation, weight management, and metabolic health. This medication works by mimicking the GLP-1 and GIP hormones, helping to regulate insulin release, lower glucagon levels, slow stomach emptying, and reduce appetite.

Compounded Tirzepatide + B12