Important Safety Information

Biest 50:50 Topical Lotion — Important Safety Information

Important safety information for compounded Biest topical lotion — how to apply, transfer precautions, estrogen-related warnings, and side effects.

Last reviewed:

Biest 50:50 Topical Lotion is a compounded product prepared by a U.S.-licensed compounding pharmacy following an individualized medical evaluation. Compounded drugs are not reviewed by the FDA for safety or effectiveness. This summary does not replace guidance from your prescribing clinician.

How to use

  • Apply the measured dose to clean, dry, intact skin (such as the inner arm or inner thigh), exactly as prescribed. Rotate application sites.
  • Allow the lotion to absorb fully and wash your hands thoroughly after applying.
  • Do not apply to the breasts or to irritated or broken skin, and do not exceed the prescribed dose.

Avoid transfer to others

  • Skin-to-skin contact can transfer estrogen to others. Let the lotion dry and cover the area with clothing.
  • Keep children and pets away from the application site.

Before you start

  • Tell your clinician about your full medical history, allergies, and all medications and supplements you take.
  • Do not use if you are pregnant, may be pregnant, or are breastfeeding.
  • Share any history of blood clots, stroke, heart attack, breast or uterine cancer, liver disease, or unexplained vaginal bleeding.

Important warnings

  • Estrogens may increase the risk of blood clots, stroke, and certain cancers. When you have a uterus, estrogen is generally prescribed together with a progestogen to help protect the uterine lining.
  • Seek emergency care (call 911) for sudden chest pain, shortness of breath, pain or swelling in a leg, sudden severe headache, vision changes, or weakness, numbness, or trouble speaking.

Possible side effects

  • Application-site reactions, breast tenderness, headache, nausea, bloating, mood changes, or vaginal spotting.
  • Report any unusual or persistent side effects to your clinician promptly.

Precautions

  • Store as directed and keep out of reach of children. Do not stop or change your dose on your own.

You are encouraged to report negative side effects of prescription products to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

This information is not comprehensive. Please reach out to your EOS Health-affiliated provider if you have any questions or concerns.

View full Prescribing Information →

You are encouraged to report negative side effects of prescription products to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.