Important Safety Information

AnagenRx for Women — Important Safety Information

Compounded topical minoxidil + tretinoin + melatonin. Avoid in pregnancy. Possible scalp irritation.

Last reviewed:

Compounded drugs are permitted to be prescribed under federal law, but are not FDA-approved and do not undergo FDA safety, effectiveness, or manufacturing review. Your EOS Health-affiliated provider may recommend this medication based on your individual medical evaluation.

AnagenRx for Women is a compounded topical scalp treatment containing topical minoxidil, topical tretinoin, and topical melatonin. Important safety information for each active ingredient is provided below.

Topical Minoxidil

Who should not use topical minoxidil?

  • You have a known allergic reaction to topical minoxidil
  • You are pregnant or trying to become pregnant
  • Your scalp is red, inflamed, infected, irritated, or painful

How to use

Apply directly to the affected area on the scalp once daily in the evening, or as specified by your provider. Do not exceed 1 mL. Allow product to dry completely before bed. Wash hands after applying. Avoid letting product drip onto the face.

Most serious side effects

If experiencing a medical emergency, call 911.

  • Chest pain, rapid heartbeat, faintness, or dizziness
  • Sudden, unexplained weight gain
  • Swelling of hands or feet
  • Scalp irritation or redness
  • Unwanted facial hair growth
  • Inflammatory reaction with blistering

Most common side effects

  • Itching
  • Skin irritation

Topical Tretinoin

Who should not use tretinoin?

  • You have a known allergic reaction to tretinoin
  • You are pregnant or trying to become pregnant. When prescribed as an oral medication, tretinoin was associated with miscarriage and birth defects. Topical tretinoin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

What to tell your provider

  • All medications you are using, especially other topical scalp treatments
  • Sun sensitivity — tretinoin can make scalp more sensitive to the sun and cause drying/peeling
  • Medical history of eczema, sun sensitivity, lupus, albinism, or porphyria

Most serious side effects

  • Skin discoloration
  • Inflammatory reaction with blistering

Most common side effects

  • Dryness, itching, burning, redness, peeling

Topical Melatonin

Who should not use topical melatonin?

  • Known allergic reaction to topical melatonin
  • Pregnant or trying to become pregnant

Most common side effects

  • Temporary reddening, sensitivity, itching, burning

Withholding or providing inaccurate information about your health and medical history in order to obtain treatment may result in harm, including, in some cases, death.

You are encouraged to report negative side effects of prescription products to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

This information is not comprehensive. Please reach out to your EOS Health-affiliated provider if you have any questions or concerns.