Important Safety Information

Sermorelin — Important Safety Information

Important safety information for compounded sermorelin injection — how to use, who should not use it, possible side effects, and precautions.

Last reviewed: May 14, 2026

Sermorelin prescribed through EOS Health is a compounded medication prepared by a U.S.-licensed 503A compounding pharmacy following an individualized medical evaluation. Compounded drugs are permitted to be prescribed under federal law but are not FDA-approved and do not undergo FDA safety, effectiveness, or manufacturing review. This summary does not replace guidance from your prescribing clinician.

How to use

  • Use only as directed by your EOS Health-affiliated clinician, at the prescribed dose and frequency. Sermorelin is given as a subcutaneous injection, typically at night.
  • Rotate injection sites and follow the storage, handling, and reconstitution instructions provided with your medication.
  • Do not exceed your prescribed dose, and do not share your medication or injection supplies with anyone.

Before you start

  • Tell your clinician about your full medical history and allergies, and about all medications and supplements you take.
  • Let your clinician know if you are pregnant, planning to become pregnant, or breastfeeding.
  • Mention any history of cancer or active malignancy, thyroid or pituitary conditions, or a known sensitivity to sermorelin or any ingredient in the formulation. Sermorelin is not appropriate for use during active malignancy.

Possible side effects

  • The most common side effects are injection-site reactions such as redness, swelling, pain, or itching.
  • Other reported effects may include flushing, headache, dizziness, nausea, or a feeling of restlessness.
  • Report any unusual or persistent side effects to your clinician promptly.

Allergic reactions

  • Watch for signs of an allergic reaction such as rash, itching, swelling, or difficulty breathing.
  • Seek immediate medical attention if these occur. If you are having a medical emergency, call 911.

Precautions

  • Use caution and follow your clinician's guidance if you have a history of thyroid, pituitary, or blood-sugar conditions, as growth hormone pathways can affect these systems.
  • Regular monitoring, including blood work, may be recommended during treatment.
  • Store as directed and keep out of reach of children.
  • Individual responses vary — follow professional guidance and do not adjust your dose on your own.

Drug interactions

  • Tell your clinician about all medications and supplements you take. Glucocorticoids (such as prednisone) and thyroid medications may affect how sermorelin works or complicate monitoring.

When to contact your provider

  • Reach out to your EOS Health-affiliated clinician with any questions, if side effects persist or worsen, or if you experience a reaction that concerns you.

You are encouraged to report negative side effects of prescription products to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

This information is not comprehensive. Please reach out to your EOS Health-affiliated provider if you have any questions or concerns.