3-in-1 Hair Growth Oral Tablets — Important Safety Information

What is in this tablet?

Each tablet is a compounded oral formulation containing minoxidil 5 mg, finasteride 1.1 mg, and biotin 1 mg. Minoxidil and finasteride are individually well-studied prescription medications; biotin is a B vitamin. This specific combination is compounded and is not FDA-approved as a combination product. Minoxidil tablets are FDA-approved to treat high blood pressure — use for hair loss is off-label.

Who should not take it?

• Women who are or may become pregnant, and anyone who is breastfeeding.
• Children.
• Anyone with a known allergy to minoxidil, finasteride, or biotin.
• Anyone with a pheochromocytoma, significant heart disease, heart failure, pericardial disease, low blood pressure, or significant kidney impairment — discuss your full history with your provider before starting.

Pregnancy warning

Finasteride can cause abnormalities of the external genitalia of a male fetus. Women who are or may become pregnant should not take this medication or handle crushed or broken tablets, as finasteride can be absorbed through the skin.

How should I take it?

Take one tablet by mouth once daily, with or without food, exactly as prescribed. Do not take more than prescribed. Hair growth is slow: your clinician will typically reassess your response after several months of consistent daily use, and continued use is required to maintain any benefit. If treatment is stopped, hair gained during treatment is generally lost over the following months.

Minoxidil (oral)

• Oral minoxidil is a potent vasodilator. Even at low doses it can cause lightheadedness, dizziness, a faster heart rate, headache, or fluid retention with swelling of the ankles, feet, or face.
• Sudden, unexplained weight gain can signal fluid retention and should be reported to your provider promptly.
• Unwanted hair growth on the face and body (hypertrichosis) is a known dose-related effect and reverses after stopping.
• A temporary increase in shedding is common in the first weeks as follicles cycle.
• Minoxidil tablets carry a boxed warning for pericardial effusion — fluid around the heart, which can progress to tamponade — and for the potential to worsen angina. These events are associated primarily with the higher doses used for hypertension, but the risk is why hair-loss dosing is kept low and clinician-supervised.
• Tell your provider about all blood-pressure medications, nitrates, and other vasodilators you take, as effects can add together.

Finasteride

• Decreased sex drive, erectile difficulty, or ejaculation problems, including reduced ejaculate volume. These usually resolve after stopping, though a small number of men report persistent effects.
• Mood changes, including depression and suicidal thoughts, have been reported.
• Breast changes such as lumps, pain, enlargement, or nipple discharge — report these promptly; rare cases of male breast cancer have been reported.
• Finasteride lowers PSA (prostate-specific antigen) levels. Tell any provider who orders a PSA test that you take finasteride.

Biotin

• Biotin is generally well tolerated. The most important consideration is laboratory interference: biotin supplementation can skew results of certain blood tests, including troponin (used to diagnose heart attack), thyroid panels, and some hormone assays.
• Tell every provider and lab that you take biotin, and ask whether you should pause it before blood work.

What should I tell my EOS Health-affiliated provider?

Share all medications, supplements, and your full medical history — especially heart disease, blood-pressure problems, kidney or liver disease, prostate conditions, and depression or other mood disorders.

Most serious side effects

If experiencing a medical emergency, call 911.

• Chest pain, shortness of breath, a rapid or irregular heartbeat, or fainting.
• Sudden swelling or rapid, unexplained weight gain.
• Serious allergic reactions (rash, hives, swelling of the lips or face, trouble breathing).
• Mood changes, including depression or suicidal thoughts.
• Breast lumps, pain, enlargement, or nipple discharge.

Most common side effects

• Lightheadedness, headache, or a mildly faster heart rate.
• Mild swelling of the ankles or feet.
• Unwanted hair growth on the face or body.
• A temporary increase in shedding early in treatment.
• Sexual side effects in a small percentage of men.

You are encouraged to report negative side effects to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

This information is not comprehensive. Please reach out to your EOS Health-affiliated provider with any questions or concerns.