Important Safety Information

Progesterone Capsules — Important Safety Information

Important safety information for oral micronized progesterone capsules — how to take, warnings, side effects, and precautions.

Last reviewed:

Prescription progesterone is dispensed following an individualized medical evaluation by a licensed clinician. Certain strengths may be prepared by a licensed compounding pharmacy; compounded drugs are not reviewed by the FDA for safety or effectiveness. This summary does not replace guidance from your prescribing clinician.

How to use

  • Take by mouth exactly as prescribed, usually once daily at bedtime.
  • Progesterone can cause drowsiness or dizziness — taking it at bedtime is common. Do not drive or operate machinery until you know how it affects you.
  • Do not take more than prescribed or stop suddenly without speaking to your clinician.

Before you start

  • Tell your clinician about your full medical history, allergies, and all medications and supplements you take.
  • Micronized progesterone capsules may contain peanut oil — tell your clinician if you have a peanut allergy.
  • Do not use if you are pregnant (unless specifically directed) or breastfeeding without clinician guidance.
  • Share any history of blood clots, stroke, liver disease, breast cancer, or unexplained vaginal bleeding.

Important warnings

  • Hormone therapy may increase the risk of blood clots and stroke in some people. Report warning signs promptly.
  • Seek emergency care (call 911) for sudden chest pain, shortness of breath, pain or swelling in a leg, sudden severe headache, vision changes, or weakness, numbness, or trouble speaking.

Possible side effects

  • Drowsiness, dizziness, breast tenderness, headache, bloating, mood changes, or vaginal spotting.
  • Report any unusual or persistent side effects to your clinician promptly.

Precautions

  • Store as directed and keep out of reach of children. Do not adjust your dose on your own.

You are encouraged to report negative side effects of prescription products to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

This information is not comprehensive. Please reach out to your EOS Health-affiliated provider if you have any questions or concerns.

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You are encouraged to report negative side effects of prescription products to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.